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TWO2® kickstarts the stalled healing process. Non-healing wounds that stall in the inflammatory phase lack adequate oxygen, which prevents essential enzymic production responsible for cellular metabolism, collagen production and immune response to fight infection.


TWO2® provides the highest penetration of oxygen into the wounded tissue through an oxygen partial pressure of approximately 800 mmHg. The extra availability of oxygen provides fuel for ATP synthesis and propels the wound out of the inflammatory phase and restores a robust healing pathway.


The chamber can be used in conjunction with either conventional compression dressings (CCD) or UNNA boots. The chamber can also be used over total contact casts (TCC) when treating diabetic foot ulcers (DFUs).

TWO2 Extremity Chamber

    • Targeted treatment:
      • Topical Wound Oxygen (TWO2®) therapy allows for targeted treatment, utilizing cyclical pressurized oxygen applied directly to the wound site.
    • Any time, anywhere:
      • Patients self-administer the therapy in the comfort of their own homes while watching TV or reading a book.
    • Available in two sizes
      • The medium chamber easily accommodates wounds on the lower two thirds of the leg. Meanwhile, the larger chamber is designed to fit over the patient’s knee, allowing treatment of larger limbs and venous leg ulcers (VLUs).

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